The Apothecary Diaries Season 2
薬屋のひとりごと 第2期
Kusuriya no Hitorigoto 2nd Season
Binge-ready
Finished airing — 24 episodes, ready to binge.
- Format
- TV
- Season
- Winter 2025
- Studio
- TOHO animation STUDIO, OLM
- Based on
- Light novel
- Episode length
- 24 min
- Started
- 10 Jan 2025
- Ended
- 4 Jul 2025
- Score
- 88/100
Drama Mystery Female Protagonist Medicine Royal Affairs Detective Historical Politics Ancient China Foreign
Using her wit and vast knowledge of medicines and poisons alike, Maomao played a pivotal role in solving a series of mysteries and conspiracies that plagued the imperial court. Having recently come to terms with the secrets of her parents, she returns to fulfill her normal duties on behalf of the emperor's highest-ranking consorts. Maomao also works alongside the eunuch Jinshi to better the consorts' many ladies-in-waiting, including helping them learn to read. However, with the arrival of a merchant caravan comes a new wave of intrigue. A pattern of strange coincidences involving the visitors and their wares unsettles Maomao, driving her to investigate the puzzling circumstances behind the convoy. As dangers from both outside and within threaten the balance between the imperial concubines, Maomao continues to utilize her cunning and medical expertise to keep the women safe from harm. (Source: MAL Rewrite)
Where to watch
Opening and ending songs
- Opening 1 Hyakka Ryouran Lilas Ikuta (episodes 1-12) Watch ↗
- Opening 2 Kusushiki Mrs. GREEN APPLE (episodes 13-24) Watch ↗
- Ending 1 Shiawase no Recipe Dai Hirai (episodes 1-12) Watch ↗
- Ending 2 Hitorigoto Omoinotake (episodes 13-24) Watch ↗
Song data from AnimeThemes.
Source material
The Apothecary Diaries ↗ · 薬屋のひとりごと
Novel · Still publishing · 2014
Source: AniList and MangaDex (publication details only).
Credits, releases and news
Staff
- Director
- Akinori Fudesaka
- Original creator
- Hyūganatsu
- Series Composition
- Norihiro Naganuma
- Script
- Misuzu Chiba, Hitomi Ogawa, Yūko Kakihara
- Character Design
- Yukiko Nakatani
- Music
- Kevin Penkin, Arisa Okehazama, Satoru Kōsaki
- Art Director
- Katsumi Takao
- Chief Animation Director
- Atsuko Nakajima, Yukiko Nakatani, Asami Watanabe
Home video releases
- 24 Nov 2026 The Apothecary Diaries - Season 2 [SteelBook] (Blu-ray)
- 10 Nov 2026 The Apothecary Diaries - Season 2 (Blu-ray)
Latest news
- 12 Jul 2025 Japanese Animation TV Ranking, June 30-July 6
- 7 Jul 2025 Japanese Animation TV Ranking, June 23-29
- 4 Jul 2025 The Apothecary Diaries Anime Gets New Sequel
- 21 Jun 2025 Japanese Animation TV Ranking, June 9-15
- 14 Jun 2025 Japanese Animation TV Ranking, June 2-8
Episode titles (24)
- 25. Maomao and Maomao
- 26. Caravan
- 27. Corpse Fungus
- 28. Mirrors
- 29. Moon Fairy
- 30. The Crystal Pavilion, for the Third Time
- 31. The Shrine of Choosing
- 32. The Empress Dowager
- 33. The Late Emperor
- 34. A Ghost Story
- 35. The Hunt
- 36. Ka Zuigetsu
- 37. The Baths
- 38. The Dancing Ghost
- 39. Ice
- 40. Festering Resentment
- 41. The Fox Village
- 42. Lantern Plant
- 43. Festival
- 44. The Stronghold
- 45. Taibon
- 46. Royal Guard
- 47. The Shi Clan
- 48. Beginning
Anime News Network readers rate it 8.83/10 (230 votes).
Source: Anime News Network. Full details at Anime News Network.
Main characters
-
Maomao
猫猫
Voiced by Aoi Yuuki
-
Jinshi
壬氏
Voiced by Takeo Ootsuka
-
Rouran
楼蘭
Voiced by Asami Seto
-
Gaoshun
高順
Voiced by Katsuyuki Konishi
-
Gyokuyou
玉葉妃
Voiced by Atsumi Tanezaki
-
Rifa
梨花妃
Voiced by Yui Ishikawa
Related anime
- Prequel: The Apothecary Diaries ↗
- Side story: Maomao no Hitorigoto 2nd Season ↗
- Sequel: The Apothecary Diaries Season 3 · Airing now
More like this
Airing data from AniList. Last updated 25 Oct 2026.